5 Greatest Supernatural Duos Besides the Most Iconic One, Ranked 

While the dynamic between Sam and Dean stole the show and the hearts of millions of fans around the world, the series also introduced several memorable partnerships that left a lasting impression on viewers.

Here are the five greatest Supernatural duos that showcased unique chemistry and added depth to the show.

5. Dean & Crowley

One of Supernatural's most entertaining and unexpected alliances was the partnership between Dean Winchester and the King of Hell, Crowley. Despite being on the opposite sides of the world's main battle, Dean and Crowley reluctantly teamed up several times.

The show created one of the most powerful and dynamic enemies-turned-almost-lovers duos with their witty banter, shared love of pop culture references, and mutual on-and-off respect for each other that fans couldn't get enough of.

4. Sam & Rowena

Sam Winchester's unlikely partnership with the cunning and unpredictable witch Rowena MacLeod added depth to the plot of the show and to the storylines of both characters. Rowena became Sam's mentor, teaching him valuable spells and sharing her magical knowledge, and Sam learned from her and sharpened his psychic skills.

However, their relationship wasn't just about spells and magic, as they developed such a genuine and heartfelt connection that Rowena chose Sam to be the one to kill her in her final effort to save the world.

3. Dean & Castiel

While the brotherly bond between Sam and Dean was at the heart of the series, Dean Winchester's friendship with the angel Castiel was nothing short of iconic. Throughout the series, their connection, marked by Castiel's deadpan humor and Dean's gruff charm, grew with the help of shared experiences that included rescuing each other from dire situations and coping with the losses on several occasions.

Dean and Castiel's loyalty to one another transcended the boundaries of Heaven and Earth, with their profound connection culminating in the moment Castiel sacrificed his own life to save Dean's, solidifying the characters’ place as one of the most legendary duos in television history.

2. Donna & Jody

Hunters-sheriffs Jody Mills and quirky Donna Hanscum formed a unique and endearing alliance in the Supernatural universe. Both being strong, independent women, they shared a common goal: to keep their hometown safe from the supernatural threats it faced.

Donna's comedic personality and Jody's no-nonsense attitude made for a delightful pair who not only went on supernatural adventures together but also created a safe haven where young people could develop their skills and find refuge.

1. Bobby & Rufus

Bobby Singer and Rufus Turner, two seasoned hunters with a shared history, brought gravitas and humor to their team. Despite their habit of getting on each other's nerves, Bobby and Rufus are known for their unwavering support for and trust in each other.

Whether they were on the hunt for monsters or delving into the supernatural lore, Bobby and Rufus' partnership provided the universe of Supernatural with profound storylines and showed the world the enormous level of trust that two people can share.